Author

J. Zha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

C. Wang· 2 shared A. Li· 1 shared A. Mironov· 1 shared A. Sali· 1 shared B. Raveh· 1 shared C. Jorgensen· 1 shared C. Kesselman· 1 shared C. R. Below· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

C. Wang

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5 papers

Recent·Most cited

Distinct steady-state properties and TNF responses of epithelial long myosin light chain kinase (MLCK) splice variants

S. D. Chanez-Paredes, S. Abtahi, J. Zha, L. Zuo, W. He, J. R. Turner

The paper identifies the Ig3 domain of MLCK1 as critical for perijunctional localization and barrier function, showing it can limit TNF-induced barrier loss in Crohn's disease.

bioRxiv · Oct 13, 2022 · PreprintCell Biology

Single-Cell RNA-seq of Heart Reveals Intercellular Communication Drivers of Myocardial Fibrosis in Diabetic Mice

Z. Zhang, W. Li, X. Lou, Y. Zha, J. Zha, L. Hong, Z. Xie, S. Yang, C. Wang, J. An, S. Qiao

This study uses single-cell RNA-seq to identify intercellular communication drivers of myocardial fibrosis in diabetic mice, highlighting key ligand-receptor interactions and fibroblast subpopulations involved in fibrosis.

bioRxiv · Jun 29, 2022Cell Biology

Pancreatic ductal adenocarcinoma cells employ integrin α6β4 to form hemidesmosomes and regulate cell proliferation

J. D. Humphries, J. Zha, J. Burns, J. A. Askari, C. R. Below, M. R. Chastney, M. C. Jones, A. Mironov, D. Knight, D. A. O'Reilly, M. J. Dunne, D. R. Garrod, C. Jorgensen, M. J. Humphries

This study identifies integrin α6β4 and hemidesmosomes as critical for PDAC cell proliferation and ECM organization, with implications for therapeutic targeting.

bioRxiv · Aug 19, 2021Cancer Biology

Bayesian metamodeling of complex biological systems across varying representations

B. Raveh, L. Sun, K. L. White, T. Sanyal, J. Tempkin, D. Zheng, K. Bharath Pilla, J. Singla, C. Wang, J. Zha, A. Li, N. A. Graham, C. Kesselman, R. C. Stevens, A. Sali

This paper introduces Bayesian metamodeling to integrate diverse models of biological systems, demonstrating its application to glucose-stimulated insulin secretion in pancreatic β-cells.

bioRxiv · Mar 29, 2021Cell Biology

HSP-4/BiP expression in secretory cells is regulated by a lineage-dependent differentiation program and not by the unfolded protein response

J. Zha, J. Alexander-Floyd, T. Gidalevitz

The paper shows that HSP-4/BiP expression in secretory cells is lineage-dependent and not controlled by the UPR, using C. elegans as a model.

bioRxiv · Aug 9, 2018Cell Biology