Author

M. R. Junttila

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Daemen· 1 shared A. K. Katakam· 1 shared A. Lima· 1 shared A. N. Lima· 1 shared A. Pribluda· 1 shared B. Haley· 1 shared B. Kruspig· 1 shared C. Miller· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Daemen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ERBB signalling contributes to immune evasion in KRAS-driven lung adenocarcinoma

S. Laing, B. Kruspig, R. Shaw, L. Officer-Jones, S. Edwards, D. McKinven, Y.-C. Hsieh, I. Powley, N. Brady, R. Pennie, R. Kwan, A. Lima, S. Myrta, M. Periyasamy, I. C. Dye, , D. J. Murphy

The paper investigates how ERBB signaling contributes to immune evasion in KRAS-driven lung adenocarcinoma using a novel mouse model and finds that transient ERBB blockade can restore immune surveillance when combined with PD1 blockade.

bioRxiv · Jul 24, 2023 · PreprintCancer Biology

G9a methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation

A. Pribluda, A. Daemen, A. N. Lima, X. Wang, M. Hafner, C. Poon, Z. Modrusan, A. K. Katakam, O. Foreman, J. Eastham, J. Hung, B. Haley, J. T. Garcia, E. L. Jackson, M. R. Junttila

This study shows G9a methyltransferase regulates Wnt signaling in lung development and tumor progression by controlling β-catenin transcriptional activity, and its inhibition prevents KrasG12D lung cancer.

bioRxiv · Apr 20, 2020 · PreprintCancer Biology