The GHB analogue HOCPCA improves sensorimotor function after MCAO via CaMKIIα
N. Griem-Krey, A. B. Klein, B. H. Clausen, M. R. Namini, P. V. Nielsen, H. Chin-Cheng, C. Orset, D. Vivien, A. N. Clarkson, K. L. Lambertsen, P. Wellendorph
The paper shows HOCPCA, a GHB ligand, improves sensorimotor function after stroke in mice by modulating CaMKII signaling and reducing aberrant activity.
bioRxiv · Mar 10, 2022 · PreprintPharmacology & Toxicology