Author

A. N. Clarkson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. B. Klein· 2 shared N. Griem-Krey· 2 shared P. Wellendorph· 2 shared A. Bach· 1 shared A. S. G. Larsen· 1 shared B. Frolund· 1 shared B. H. Clausen· 1 shared B. R. Kornum· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

A. B. Klein

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The GHB analogue HOCPCA improves sensorimotor function after MCAO via CaMKIIα

N. Griem-Krey, A. B. Klein, B. H. Clausen, M. R. Namini, P. V. Nielsen, H. Chin-Cheng, C. Orset, D. Vivien, A. N. Clarkson, K. L. Lambertsen, P. Wellendorph

The paper shows HOCPCA, a GHB ligand, improves sensorimotor function after stroke in mice by modulating CaMKII signaling and reducing aberrant activity.

bioRxiv · Mar 10, 2022 · PreprintPharmacology & Toxicology

GHB confers neuroprotection by stabilizing the CaMKIIα hub domain

U. Leurs, A. B. Klein, E. D. McSpadden, N. Griem-Krey, S. M. Solbak, J. Houlton, I. S. Villumsen, S. B. Vogensen, L. Hamborg, S. J. Gauger, L. B. Palmelund, A. S. G. Larsen, M. A. Shehata, C. D. Kelstrup, J. V. Olsen, , P. Wellendorph

This study shows that GHB stabilizes the CaMKII hub domain, providing neuroprotection in cellular and mouse models.

bioRxiv · Sep 28, 2020 · PreprintBiochemistry