Cancer BiologybioRxivPreprint
Trellis Single-Cell Screening Reveals Stromal Regulation of Patient-Derived Organoid Drug Responses
M. Ramos Zapatero, A. Tong, J. Sufi…·C. J. Tape
The paper develops Trellis, a method to analyze single-cell drug responses in PDOs and CAFs, revealing patient-specific apoptosis and CAF-mediated chemoprotection via YAP signaling.
DOI 10.1101/2022.10.19.512668