Author

M. Ravichandran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Rao· 1 shared C. Arrowsmith· 1 shared C. H. Arrowsmith· 1 shared H. Ouyang· 1 shared H. Zheng· 1 shared I. Franzoni· 1 shared L. Aravind· 1 shared L. Halabelian· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Rao

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2 papers

Recent·Most cited

Structural basis of HMCES interactions with DNA reveals multivalent substrate recognition

L. Halabelian, M. Ravichandran, Y. Li, H. Zheng, L. Aravind, A. Rao, C. H. Arrowsmith

This study reports crystal structures of the HMCES SRAP domain bound to DNA-damage substrates, revealing how HMCES recognizes and binds different DNA structures for crosslinking.

bioRxiv · Jan 13, 2019Biochemistry

Identification and Structure-Activity Relationship of HDAC6 Zinc-finger Ubiquitin Binding Domain Inhibitors

R. Ferreira de Freitas, R. Harding, I. Franzoni, M. Ravichandran, M. K. Mann, H. Ouyang, M. Lautens, V. Santhakumar, C. Arrowsmith, M. Schapira

The paper identifies HDAC6 ZnF-UBD inhibitors and describes their structure-activity relationships, revealing key binding features and potential for further optimization.

bioRxiv · Feb 20, 2018Biophysics