Author

R. Harding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Anttila· 1 shared C. Arrowsmith· 1 shared C. Bennett· 1 shared C. C. dela Sena· 1 shared C. H. Arrowsmith· 1 shared C. Zepeda· 1 shared D. Amann-Zalcenstein· 1 shared D. Barsyte-Lovejoy· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperImmunology

C. Anttila

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Spatial analysis of Hofbauer cell transcriptome, distribution and morphology in placentas exposed to Plasmodium falciparum

R. Ataide, R. Harding, M. Dharmaratne, Y. Chen, K. Fielding, L. Whitehead, K. Rogers, C. Anttila, L. Ling, P. Hickey, D. Amann-Zalcenstein, E. Moya, G. Mhango, S. Kamiza, L. Randall, , S.-R. Pasricha

The paper examines spatial transcriptomic and proteomic profiles of Hofbauer cells in placentas with and without past Plasmodium falciparum infection, finding no significant differences in HBC features but reduced fetal vessel development in infected placentas.

bioRxiv · Nov 27, 2023 · PreprintImmunology

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

M. M. Szewczyk, Y. Ishikawa, S. Organ, N. Sakai, F. Li, S. Ackloo, M. S. Eram, D. Dilworth, H. Fukushi, R. Harding, C. C. dela Sena, T. Sugo, K. Hayashi, D. Macleod, C. Zepeda, , D. Barsyte-Lovejoy

This study identifies a PRMT7 inhibitor and shows its effect on arginine methylation of stress proteins, linking PRMT7 to cellular stress response.

bioRxiv · Mar 15, 2019Biochemistry

Identification and Structure-Activity Relationship of HDAC6 Zinc-finger Ubiquitin Binding Domain Inhibitors

R. Ferreira de Freitas, R. Harding, I. Franzoni, M. Ravichandran, M. K. Mann, H. Ouyang, M. Lautens, V. Santhakumar, C. Arrowsmith, M. Schapira

The paper identifies HDAC6 ZnF-UBD inhibitors and describes their structure-activity relationships, revealing key binding features and potential for further optimization.

bioRxiv · Feb 20, 2018Biophysics