M. S. Dietz

Self-quenched fluorophore-DNA labels for super-resolution fluorescence microscopy

The paper introduces self-quenched fluorophore-DNA labels to reduce background signal in super-resolution microscopy, improving imaging performance in STED and SMLM.

Single-molecule imaging and molecular dynamics simulations reveal early activation of the MET receptor in situ

The paper uses single-molecule imaging and molecular dynamics simulations to study early MET receptor activation in situ, revealing structural dynamics and a refined dimer model.

Biased activation of the receptor tyrosine kinase HER2

This study measures HER2 activation in live cells using single-molecule tracking and finds ligand-specific activation strength and temporal profiles.

Dynamic in situ confinement triggers ligand-free neuropeptide receptor signaling

This study shows that dynamic in situ confinement of the Y2R receptor triggers ligand-independent signaling through cytosolic calcium increases, cell spreading, and migration.

Relevance of Circulating Hybrid Cells as a Non-Invasive Biomarker for Myriad Solid Tumors

This study identifies circulating hybrid cells (CHCs) as a novel biomarker for metastatic solid tumors, showing they outnumber CTCs and exhibit tumor-initiating properties across multiple cancer types.

Visualizing multi-protein patterns at the synapse of neuronal tissue with DNA-assisted single-molecule localization microscopy

This paper introduces a method to visualize multiple proteins at synapses using DNA-assisted single-molecule localization microscopy, enabling high-resolution imaging of neuronal tissue sections.