The beta 6 Integrin Negatively Regulates TLR7-Mediated Epithelial Immunity via Autophagy During Influenza A Virus Infection
M. Smith, V. A. Meliopoulos, S. Tan, T. Bub, P. H. Brigleb, B. Sharp, J. C. Crawford, M. S. Prater, S. M. Pruett-Miller, S. Schultz-Cherry
This study shows that beta 6 integrin suppresses TLR7-mediated epithelial immunity during influenza A virus infection by promoting autophagy and altering TLR7 trafficking.
bioRxiv · Aug 28, 2023 · PreprintImmunology