Synthetic Agonist of Growth Hormone-Releasing Hormone as Novel Treatment for Heart Failure with Preserved Ejection Fraction
R. A. Dulce, R. M. Kanashiro-Takeuchi, L. M. Takeuchi, A. G. Salerno, S. Kulandavelu, W. Balkan, M. S. Zuttion, R. Cai, A. V. Schally, J. M. Hare
This paper tests a synthetic GHRH agonist, MR-356, in a mouse model of HFpEF, showing it prevents and reverses cardiac remodeling and dysfunction.
bioRxiv · Feb 28, 2020 · PreprintCell Biology