Author

M. Sakuma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Organism:E. coli· 1

Frequent Co-Authors

A. Aiba· 1 shared A. Green· 1 shared A. Taylor· 1 shared D. Heyes· 1 shared H. Higuchi· 1 shared H. Noji· 1 shared H. Ueno· 1 shared K. Miyazaki· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

A. Aiba

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Author profile →

4 papers

Recent·Most cited

Mechanistic implications of the ternary complex structural models for the photoenzyme protochlorophyllide oxidoreductase.

A. Taylor, S. Zhang, L. Johannissen, M. Sakuma, R. Phillips, A. Green, S. Hay, D. Heyes, N. Scrutton

The paper investigates structural models of the POR-Pchlide-NADPH ternary complex and proposes an alternative model based on mutagenesis and computational analysis, identifying key residues involved in catalysis.

bioRxiv · Sep 4, 2023Biochemistry

Genetic perturbation enhances functional heterogeneity in alkaline phosphatase

M. Sakuma, S. Honda, H. Ueno, K. Miyazaki, N. Tokuriki, H. Noji

This study quantifies functional heterogeneity in wild-type and mutant alkaline phosphatase, finding that genetic perturbations increase heterogeneity and correlate with promiscuous activities.

bioRxiv · Nov 25, 2021 · PreprintBiochemistry

Quantitative Detection of Cell Activity by Measuring the Fluctuation of Intracellular Motility

M. Sakuma, Y. Kondo, H. Higuchi

The paper measures cell activity by analyzing intracellular motility fluctuations and finds that damage reduces these fluctuations across cell types.

bioRxiv · Nov 22, 2019 · PreprintCell Biology

Rac-dependent signaling from keratinocytes promotes differentiation of intradermal white adipocytes

T. Ueyama, M. Sakuma, M. Nakatsuji, T. Uebi, T. Hamada, A. Aiba, N. Saito

This study shows that Rac-dependent signaling from keratinocytes promotes white and brown adipocyte differentiation through paracrine BMP2 and FGF21 pathways.

bioRxiv · Nov 19, 2018Cell Biology