Author

S. Honda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:E. coli· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

H. Noji· 2 shared A. Ooishi· 1 shared H. Imamura· 1 shared H. Masaki· 1 shared H. Suzuki· 1 shared H. Ueno· 1 shared J. Endo· 1 shared K. Hattori· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBiochemistry

H. Noji

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Designing monomeric IFNγ: the significance of domain-swapped dimer structure in IFNγ immune responses

Y. Goto, T. Miyafusa, S. Honda

This study designs a monomeric IFNγ by modifying its domain-swapped dimer structure, showing it retains a similar balance of immunostimulatory and immunosuppressive gene expression as wild-type IFNγ.

bioRxiv · Feb 18, 2024Biochemistry

Heart generation via blastocyst complementation in Mesp1/2-deficient mice

Y. Abe, T. Sadahiro, R. Fujita, Y. Yamada, T. Akiyama, K. Nakano, S. Honda, Y. Tanimoto, H. Suzuki, S. Mizuno, S. Takahashi, T. Yamaguchi, H. Masaki, K. Hattori, T. Mashimo, M. Ieda

This study generates functional adult hearts in Mesp1/2-deficient mice using blastocyst complementation with pluripotent stem cells, showing successful derivation of all cardiovascular lineages from exogenous cells.

bioRxiv · Nov 8, 2023 · PreprintCell Biology

Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies

H. Imamura, A. Ooishi, S. Honda

This study shows that acid denaturation of IgG1 antibodies leads to compaction, reducing their size and suggesting non-canonical structures may have biological significance.

bioRxiv · Sep 19, 2022Biophysics

Genetic perturbation enhances functional heterogeneity in alkaline phosphatase

M. Sakuma, S. Honda, H. Ueno, K. Miyazaki, N. Tokuriki, H. Noji

This study quantifies functional heterogeneity in wild-type and mutant alkaline phosphatase, finding that genetic perturbations increase heterogeneity and correlate with promiscuous activities.

bioRxiv · Nov 25, 2021 · PreprintBiochemistry

Dynamics of peripheral blood flow across sleep stages

Z. Fan, Y. Suzuki, L. Jiang, S. Okabe, S. Honda, J. Endo, T. Watanabe, T. Abe

This study compares pulse rate variability (PRV) and heart rate variability (HRV) across sleep stages using peripheral blood flow measurements, finding PRV provides similar information to HRV and may offer additional insights.

bioRxiv · Nov 4, 2021 · PreprintPhysiology

Multi-dimensional digital bioassay platform based on an air-sealed femtoliter reactor array device

S. Honda, Y. Minagawa, H. Noji, K. V. Tabata

This paper introduces a multi-dimensional digital bioassay platform for analyzing single molecules, demonstrating its ability to perform multi-conditional and multi-parametric assays with high stability and resolution.

bioRxiv · Oct 25, 2020Biophysics