NCLX prevents cell death during adrenergic activation of the brown adipose tissue
E. A. Assali, A. E. Jones, M. Veliova, M. Taha, N. Miller, M. Shum, M. F. Oliveira, G. Las, M. Liesa, I. Sekler, O. S. Shirihai
This study identifies NCLX as a critical mitochondrial Na+/Ca2+ exchanger that prevents cell death during adrenergic activation of brown adipose tissue by mitigating Ca2+ overload.
bioRxiv · Nov 6, 2018Physiology