The mRNA-binding protein HuR is a kinetically-privileged electrophile sensor
J. R. Poganik, A. Van Hall-Beauvais, M. J. C. Long, M. T. Disare, Y. Zhao, Y. Aye
This study identifies HuR as a kinetically-privileged sensor of the electrophile HNE, showing its role in regulating Nrf2-driven antioxidant responses through cysteine C13.
bioRxiv · Apr 7, 2020Biochemistry