Downregulation of Semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis
M. Kume, H. Koguchi-Yoshioka, S. Nakai, Y. Matsumura, A. Tanemura, K. Yokoi, S. Matsuda, Y. Nakamura, N. Otani, M. Taminato, K. Tomita, T. Kubo, M. Wataya-Kaneda, A. Kumanogoh, M. Fujimoto, R. Watanabe
This study shows that downregulation of Sema4A in keratinocytes is associated with non-lesional psoriasis features and that Sema4A regulates skin homeostasis and inflammation.
bioRxiv · Apr 2, 2024 · PreprintImmunology