Y. Matsumura

The paper investigates the virological features of the SARS-CoV-2 EG.5.1 variant, finding its fitness and antiviral sensitivity comparable to XBB.1.5, with structural differences in spike proteins.

This study uses genomic surveillance of E. coli from Ugandan fecal sludge and sewage to track antimicrobial resistance patterns and identify key resistance determinants.

The paper traces the nationwide spread of β-lactam resistance in pneumococci through horizontal transmission of a specific PBP1A variant, highlighting its role in resistance emergence.

This study shows that candies with persimmon-derived tannin reduce SARS-CoV-2 delta variant titers in saliva from healthy volunteers and patients with COVID-19.

This study characterizes the genetic contexts of blaCTX-M genes in environmental Escherichia coli isolates from river water in Japan, revealing diverse chromosomal and plasmid-associated configurations.

The paper shows that glutamine deficiency in cancer cells prevents p53 activation by rRNA synthesis inhibitors, promoting survival during nutrient stress.

This study identifies rare carbapenemases in environmental Enterobacterales from Japan, revealing their genetic contexts and plasmid locations.

This paper identifies CD73 as the antigen of a monoclonal antibody generated by exosome immunization and shows its antibody-drug conjugate has antitumor effects on glioblastoma cell lines.

This paper shows nasal delivery of a camelid single-domain antibody reduces SARS-CoV-2 titers in hamsters without weight loss or cytokine induction.

This paper develops a thrombolytic fusion protein, AMU1114, that selectively targets insoluble fibrin, reducing systemic side effects compared to tPA and UK.

This study shows TMEM180 promotes colorectal cancer growth by enhancing glucose and glutamine metabolism, despite not affecting oxygen consumption or phosphorylation.

The paper compares 12 SARS-CoV-2 molecular assays using respiratory samples, finding some have 100% specificity and high sensitivity, with recommendations for use with internal controls.

This paper identifies TMEM180 as a 12-transmembrane protein with extracellular N- and C-termini and a conserved cation-binding site, suggesting it functions as a cation symporter in colorectal cancer.

This study determines a more accurate estimate of the hemoglobin glycation rate constant (kg) by comparing MRBC calculated from HbA1c, AG, and kg to traditional 51Cr measurements.