Author

M. Tolstrup

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 2 Assay:flow cytometry· 1

Frequent Co-Authors

O. S. Sogaard· 3 shared J. D. Gunst· 2 shared L. Ostergaard· 2 shared A. G. Oliver· 1 shared A. H. F. Andersen· 1 shared A. Holleufer· 1 shared A. Laustsen· 1 shared C. Erikstrup· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

O. S. Sogaard

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3 papers

Recent·Most cited

Nanobody-mediated Complement Activation to Kill HIV-infected Cells

M. L. Pedersen, D. V. Pedersen, M. B. L. Winkler, H. G. Olesen, O. S. Sogaard, L. Ostergaard, N. S. Laursen, A. H. F. Andersen, M. Tolstrup

This paper develops a bispecific complement engager to target HIV-1-infected cells, enhancing complement-mediated killing through C3 deposition and CDC.

bioRxiv · Jun 9, 2022Immunology

Distinct SARS-CoV-2 sensing pathways in pDCs driving TLR7-antiviral vs. TLR2-immunopathological responses in COVID-19

R. M. van der Sluis, L. B. Cham, A. G. Oliver, K. R. Gammelgaard, J. G. Pedersen, M. Idorn, U. Ahmodov, S. S. Hernandez, E. Cemalovic, S. H. Godsk, J. Thyrsted, J. D. Gunst, S. D. Nielsen, J. j. Jorgensen, T. W. Bjerg, , M. R. Jakobsen

The paper shows that pDCs use TLR7 for antiviral responses and TLR2 for inflammatory responses to SARS-CoV-2, with neuropilin-1 inhibiting antiviral IFNs.

bioRxiv · Nov 23, 2021 · PreprintImmunology

SARS-CoV-2 Elicits Robust Adaptive Immune Responses Regardless of Disease Severity

S. S. F. Nielsen, L. K. Vibholm, I. Monrad, R. Olesen, G. S. Frattari, M. H. Pahus, J. F. Hojen, J. D. Gunst, C. Erikstrup, A. Holleufer, R. Hartmann, L. Ostergaard, O. S. Sogaard, M. H. Schleimann, M. Tolstrup

This study characterizes adaptive immune responses in SARS-CoV-2 recovered patients, finding robust antibody and T-cell responses across disease severities.

bioRxiv · Oct 8, 2020Immunology