FAP-retargeted Ad5 enables in vivo gene delivery to stromal cells in the tumor microenvironment
K. P. Hartmann, M. van Gogh, P. C. Freitag, F. Kast, G. Nagy-Davidescu, L. Borsig, A. Plueckthun
This study develops a FAP-targeted adenovirus for delivering therapeutics to cancer-associated fibroblasts, showing reduced tumor growth in vivo.
bioRxiv · Dec 19, 2022 · PreprintBiochemistry