A. Gyoergy

The solute carrier MFSD1 decreases β1 integrins activation status and thus tumor metastasis

This study shows that MFSD1 reduces β1 integrin activation, thereby suppressing tumor metastasis in a mouse model.

Cell division in tissues enables macrophage infiltration

The paper shows that cell division in Drosophila embryos enables macrophage invasion by disassembling focal adhesions, allowing nuclear movement and tissue penetration.

A genetic program boosts mitochondrial function to power macrophage tissue invasion

The paper identifies Atossa as a genetic program that enhances mitochondrial function in Drosophila macrophages to support tissue invasion through increased oxidative phosphorylation.

Cortical actin properties controlled by Drosophila Fos aid macrophage infiltration against surrounding tissue resistance

This study identifies Drosophila Fos as a regulator of cortical actin dynamics in macrophages, enabling tissue infiltration by counteracting tissue resistance.

A conserved MFS orchestrates a subset of O-glycosylation to facilitate macrophage dissemination and tissue invasion

The paper identifies Minerva, an MFS protein, as a conserved regulator of O-glycosylation that facilitates macrophage dissemination and tissue invasion in Drosophila and vertebrates.