Author

M. W. Brown

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:phylogenetics / evolution· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Organism:human· 1

Frequent Co-Authors

A. K. Tice· 3 shared D. J. G. Lahr· 2 shared A. E. Dolan· 1 shared A. G. B. Simpson· 1 shared A. Heiss· 1 shared A. J. Roger· 1 shared A. Ke· 1 shared A. L. Porfirio-Sousa· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersEvolutionary Biology

A. K. Tice

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Amoebozoan testate amoebae illuminate the diversity of heterotrophs and the complexity of ecosystems throughout geological time

A. L. Porfirio-Sousa, A. K. Tice, L. Morais, G. M. Ribeiro, Q. Blandenier, K. Dumack, Y. Eglit, N. W. Fry, M. B. Gomes E Souza, T. C. Henderson, F. Kleitz-Singleton, D. Singer, M. W. Brown, D. J. G. Lahr

This study uses phylogenomic data and fossil records to estimate divergence times of Arcellinida and related taxa, revealing key evolutionary events in heterotrophic eukaryotes.

bioRxiv · Nov 8, 2023Evolutionary Biology

The integrin-mediated adhesome complex, essential to multicellularity, is present in the most recent common ancestor of animals, fungi, and amoebae

S. Kang, A. K. Tice, C. W. Stairs, D. J. G. Lahr, R. E. Jones, M. W. Brown

The paper shows the integrin-mediated adhesome complex existed in the common ancestor of animals, fungi, and amoebae, predating the evolution of Amoebozoa.

bioRxiv · Apr 29, 2020 · PreprintEvolutionary Biology

Phylogenomics places orphan protistan lineages in a novel eukaryotic super-group

M. W. Brown, A. Heiss, R. Kamikawa, Y. Inagaki, A. Yabuki, A. K. Tice, T. Shiratori, K. Ishida, T. Hashimoto, A. G. B. Simpson, A. J. Roger

The paper uses phylogenomic analysis to place orphan protist lineages into a novel eukaryotic super-group, CRuMs, and clarifies their relationship to Amorphea.

bioRxiv · Dec 3, 2017Evolutionary Biology

Assembly and translocation of a CRISPR-Cas primed acquisition complex

M. W. Brown, K. E. Dillard, Y. Xiao, A. E. Dolan, E. T. Hernandez, S. Dahlhauser, Y. Kim, L. R. Myler, E. Anslyn, A. Ke, I. Finkelstein

This study uses single-molecule techniques to characterize the type I-E CRISPR-Cas primed acquisition complex, revealing how Cascade, Cas3, and Cas1-Cas2 coordinate to recognize and acquire foreign DNA.

bioRxiv · Oct 26, 2017Biophysics