Author

R. E. Jones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. K. Tice· 1 shared A. V. Columbus· 1 shared C. J. Bakkenist· 1 shared C. W. Stairs· 1 shared D. Bae· 1 shared D. Ivanov· 1 shared D. J. G. Lahr· 1 shared F. P. Vendetti· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperEvolutionary Biology

A. K. Tice

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy

P. Pandya, F. P. Vendetti, J. A. El-Ghoubaira, S. Pathak, J. J. Deppas, R. E. Jones, A. V. Columbus, Y. Zhang, D. Ivanov, Z. Huang, K. M. MacDonald, S. M. Harding, R. Buj, K. M. Aird, J. H. Beumer, , C. J. Bakkenist

The paper shows that dU-rich cytoplasmic DNA inhibits STING-dependent immune responses and enhances anti-PD-L1 therapy efficacy in tumors.

bioRxiv · Apr 4, 2024 · PreprintCancer Biology

Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates

D. Bae, R. E. Jones, K. M. Piscopo, M. Tyagi, J. D. Shepherd, J. Hollien

The paper shows that IRE1-mediated degradation of Blos1 prevents mHTT aggregation by promoting endosomal microautophagy, protecting cells from toxic mHTT forms.

bioRxiv · Sep 28, 2021Cell Biology

The integrin-mediated adhesome complex, essential to multicellularity, is present in the most recent common ancestor of animals, fungi, and amoebae

S. Kang, A. K. Tice, C. W. Stairs, D. J. G. Lahr, R. E. Jones, M. W. Brown

The paper shows the integrin-mediated adhesome complex existed in the common ancestor of animals, fungi, and amoebae, predating the evolution of Amoebozoa.

bioRxiv · Apr 29, 2020 · PreprintEvolutionary Biology