Author

M. Wachsmuth-Melm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:microscopy & imaging analysis· 3 Research Focus:cell type annotation· 2 Assay:cryo-EM· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:spatial domain detection· 2 Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1

Frequent Co-Authors

P. Chlanda· 3 shared R. Bartenschlager· 2 shared S. L. Winter· 2 shared B. Cerikan· 1 shared B. S. Bodmer· 1 shared C. J. Neufeldt· 1 shared J. Makroczyova· 1 shared K. Fischer· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

P. Chlanda

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nucleocapsid condensation drives Ebola viral factory maturation and dispersion

M. Vallbracht, B. S. Bodmer, K. Fischer, S. L. Winter, L. Wendt, M. Wachsmuth-Melm, T. Hoenen, P. Chlanda

This study uses cryo-ET to show that Ebola virus nucleocapsids transition from loose helical structures to condensed cylinders, driving viral factory maturation and dispersion.

bioRxiv · Nov 6, 2023 · PreprintMicrobiology

SARS-CoV-2 nsp3-4 suffice to form a pore shaping replication organelles

L. Zimmermann, X. Zhao, J. Makroczyova, M. Wachsmuth-Melm, V. Prasad, R. Bartenschlager, P. Chlanda

The paper identifies nsp3-4 as the minimal components forming a DMV-spanning pore in SARS-CoV-2 replication organelles, critical for membrane curvature and DMV formation.

bioRxiv · Oct 21, 2022 · PreprintMicrobiology

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

S. Klein, M. Cortese, S. L. Winter, M. Wachsmuth-Melm, C. J. Neufeldt, B. Cerikan, M. L. Stanifer, S. Boulant, R. Bartenschlager, P. Chlanda

This study uses in situ cryo-electron tomography to visualize SARS-CoV-2 replication compartments and virion structure, revealing RNA filament organization and vRNP packaging mechanisms.

bioRxiv · Jun 23, 2020Microbiology