Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
C. Mazeaud, S. Pfister, J. E. Owen, H. S. Pereira, F. Charbonneau, Z. E. Robinson, A. Anton, C. L. Bemis, A. A. Sow, T. R. Patel, C. J. Neufeldt, P. Scaturro, L. Chatel-Chaix
This study identifies IGF2BP2 as a host factor hijacked by ZIKV to regulate viral replication organelle biogenesis and vRNA synthesis.
bioRxiv · Dec 8, 2023Microbiology
K. Tabata, V. Prasad, D. Paul, J.-Y. Lee, M.-T. Pham, W.-I. Twu, C. J. Neufeldt, M. Cortese, B. Cerikan, C. S. Tran, C. Luechtenborg, P. Vkovski, K. Hoermann, A. Mueller, C. Zitzmann, , R. Bartenschlager
This study identifies phosphatidic acid as critical for double membrane vesicle formation in HCV and SARS-CoV-2 replication, suggesting host-targeted PA synthesis inhibition as a therapeutic strategy.
bioRxiv · May 10, 2021Microbiology
I. L. Shytaj, M. Fares, B. Lucic, L. Gallucci, M. M. Tolba, L. Zimmermann, A. T. Ayoub, M. Cortese, C. J. Neufeldt, V. Laketa, P. Chlanda, O. T. Fackler, S. Boulant, R. Bartenschlager, M. Stanifer, , M. Lusic
This study shows that cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication in cell lines and organoids, reducing viral replication to levels comparable to uninfected cells.
bioRxiv · Mar 9, 2021Microbiology
C. Pape, R. Remme, A. Wolny, S. Olberg, S. Wolf, L. Cerrone, M. Cortese, S. Klaus, B. Lucic, S. Ullrich, M. Anders-Össwein, S. Wolf, C. Berati, C. J. Neufeldt, M. Ganter, , V. Laketa
The paper develops a semi-quantitative microscopy-based assay to detect SARS-CoV-2 specific antibodies in human sera, providing a sensitive and specific method for serological analysis.
BioEssays · Dec 30, 2020Peer-reviewedMicrobiology
W. Kamel, M. Noerenberg, B. Cerikan, H. Chen, A. I. Järvelin, M. Kammoun, J. Lee, N. Shuai, M. Garcia-Moreno, A. Andrejeva, M. J. Deery, C. J. Neufeldt, M. Cortese, M. L. Knight, K. S. Lilley, , A. Castello
The paper identifies key host and viral RNA-binding proteins involved in SARS-CoV-2 infection and shows that drugs targeting these proteins can inhibit infection.
bioRxiv · Nov 25, 2020Microbiology
F. Pahmeier, C. J. Neufeldt, B. Cerikan, V. Prasad, C. Pape, V. Laketa, A. Ruggieri, R. Bartenschlager, M. Cortese
This paper introduces a versatile reporter system that detects virus-infected cells by using protease activity and applies it to dengue virus and SARS-CoV-2.
bioRxiv · Aug 31, 2020Microbiology
C. J. Neufeldt, B. Cerikan, M. Cortese, J. Frankish, J.-Y. Lee, A. Plociennikowska, F. Heigwer, S. Joecks, S. S. Burkart, D. Y. Zander, M. Gendarme, B. El Debs, N. Halama, U. Merle, M. Boutros, , R. Bartenschlager
This study shows SARS-CoV-2 triggers a pro-inflammatory cytokine response via cGAS-STING and NF-κB in epithelial cells, which may contribute to severe disease.
bioRxiv · Jul 21, 2020Microbiology
Z. Ke, J. Oton, K. Qu, M. Cortese, V. Zila, L. McKeane, T. Nakane, J. Zivanov, C. J. Neufeldt, J. M. Lu, J. Peukes, X. Xiong, H.-G. Krausslich, S. H. W. Scheres, R. Bartenschlager, J. A. G. Briggs
This study uses cryo-electron microscopy to determine the structure, conformational flexibility, and distribution of SARS-CoV-2 spike protein trimers on intact virions.
bioRxiv · Jun 27, 2020Microbiology
S. Klein, M. Cortese, S. L. Winter, M. Wachsmuth-Melm, C. J. Neufeldt, B. Cerikan, M. L. Stanifer, S. Boulant, R. Bartenschlager, P. Chlanda
This study uses in situ cryo-electron tomography to visualize SARS-CoV-2 replication compartments and virion structure, revealing RNA filament organization and vRNP packaging mechanisms.
bioRxiv · Jun 23, 2020Microbiology