Author

T. Hoenen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

B. S. Bodmer· 2 shared M. Vallbracht· 2 shared P. Chlanda· 2 shared S. L. Winter· 2 shared A. Marzi· 1 shared B. Bhatia· 1 shared B. Bruegger· 1 shared B. E. Neubauer· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

B. S. Bodmer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nucleocapsid condensation drives Ebola viral factory maturation and dispersion

M. Vallbracht, B. S. Bodmer, K. Fischer, S. L. Winter, L. Wendt, M. Wachsmuth-Melm, T. Hoenen, P. Chlanda

This study uses cryo-ET to show that Ebola virus nucleocapsids transition from loose helical structures to condensed cylinders, driving viral factory maturation and dispersion.

bioRxiv · Nov 6, 2023 · PreprintMicrobiology

The Ebola virus VP40 matrix undergoes endosomal disassembly essential for membrane fusion

S. L. Winter, G. Golani, F. Lolicato, M. Vallbracht, K. Thiyagarajah, S. S. Ahmed, C. Luechtenborg, O. T. Fackler, B. Bruegger, T. Hoenen, W. Nickel, U. S. Schwarz, P. Chlanda

This study shows that Ebola virus VP40 matrix disassembles in endosomes due to pH changes, facilitating membrane fusion and viral entry.

bioRxiv · Aug 24, 2022 · PreprintMicrobiology

TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction

R. P. Galao, H. Wilson, K. L. Schierhorn, F. Debeljak, B. S. Bodmer, D. Goldhill, T. Hoenen, S. J. Wilson, C. M. Swanson, S. Neil

This study identifies TRIM25 and ZAP as key factors in type I interferon-mediated inhibition of Ebola virus replication by targeting the viral ribonucleoprotein complex.

bioRxiv · May 23, 2021Microbiology

Ebola virus glycoprotein domains associated with protective efficacy

B. Bhatia, W. Furuyama, T. Hoenen, H. Feldmann, A. Marzi

The paper identifies regions of the Ebola virus glycoprotein that are essential for vaccine vector replication but not for protective immunity.

bioRxiv · May 22, 2021Microbiology

Ebola virus inclusion body formation and RNA synthesis are controlled by a novel domain of NP interacting with VP35

T. Miyake, C. Farley, B. E. Neubauer, T. Beddow, T. Hoenen, D. A. Engel

This study identifies two NP domains controlling Ebola virus inclusion body formation and RNA synthesis, with the central domain interacting with VP35 to regulate these processes.

bioRxiv · Apr 6, 2020Microbiology