M. Watve

Evolution of new variants of SARS-COV-2 during the pandemic: mutation limited or selection limited?

The paper analyzes the evolution of SARS-CoV-2 variants during the pandemic, finding that variant invasion is selection limited, not mutation limited, and not a necessary cause of pandemic waves.

Reduced blood to brain glucose transport as the cause for hyperglycemia in a model 2 resolves multiple anomalies in type 2 diabetes

The paper proposes a model where reduced blood-to-brain glucose transport explains hyperglycemia in type 2 diabetes and resolves multiple anomalies not addressed by traditional insulin resistance models.

Phylogenetic diversity and activity screening of cultivable actinobacteria isolated from marine sponges and associated environments from the western coast of India

The paper studies actinobacteria from marine sponges and associated environments, identifying new species and reporting predatory behavior and antibacterial activity.

The ratio versus difference optimization and its implications for optimality theory

The paper compares ratio and difference optimization models, identifying conditions under which each is appropriate and applies them to various biological and economic examples.

Predator prey and the third beneficiary

The paper shows antibiotic-resistant bacteria benefit from predation by predatory bacteria by utilizing nutrients from lysed prey, enhancing their fitness without investing in predation machinery.

Does insulin signalling decide glucose levels in the fasting steady state?

The paper re-examines the role of insulin in glucose homeostasis using multiple approaches and concludes that insulin is necessary to reach a fasting glucose steady state but does not determine its level.

Context-dependent selection as the keystone in somatic evolution of cancer

This study evaluates models of cancer somatic evolution, finding that context-dependent selection explains epidemiological patterns better than other models.

Inferring causal pathways among three or more variables from steady-state correlations in a homeostatic system

The paper infers causal pathways among three or more variables in homeostatic systems using steady-state correlations and applies it to challenge the classical pathway in insulin resistance.

Foraging theory and the propensity to be obese: an alternative to thrift

The paper proposes a foraging optimization model to explain obesity, suggesting that reduced foraging risk in modern environments leads to increased adiposity through interactions between fear peptides and leptin.