Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
M. Karim, M. Mishra, C.-W. Lo, S. Saul, H. B. Cagirici, D. H. Nhu Tran, A. Agrawal, L. Ghita, A. Ojha, M. P. East, K. Anbro Gammeltoft, M. Kumar Sahoo, G. L. Johnson, S. Das, D. Jochmans, , S. Einav
RMC-113 inhibits PIP4K2C and PIKfyve, reversing SARS-CoV-2-induced autophagic flux impairment and showing antiviral effects.
bioRxiv · Apr 15, 2024Microbiology
X. Nuqui, L. Casalino, L. Zhou, M. Shehata, A. Wang, A. L. Tse, A. Ojha, F. L. Kearns, M. A. Rosenfeld, E. H. Miller, C. M. Acreman, S.-H. Ahn, K. Chandran, J. S. McLellan, R. E. Amaro
This study designs stabilized SARS-CoV-2 S2 immunogens using simulation-driven approaches, showing improved stability and immunogenicity.
bioRxiv · Oct 24, 2023Biophysics
J. G. Yuen, G.-R. Hwang, A. Fesler, E. Intriago, A. Pal, A. Ojha, J. Ju
Yuen and Hwang et al. developed Gem-modified miRNA mimics that show enhanced efficacy in inhibiting PDAC cell growth and tumor progression with reduced toxicity.
bioRxiv · Aug 14, 2023Cancer Biology
The paper proposes a model where reduced blood-to-brain glucose transport explains hyperglycemia in type 2 diabetes and resolves multiple anomalies not addressed by traditional insulin resistance models.
bioRxiv · Jan 19, 2022Physiology
L. Zhang, C. B. Jackson, H. Mou, A. Ojha, E. S. Rangarajan, T. Izard, M. Farzan, H. Choe
The paper compares the D614G mutation in SARS-CoV-2 spike protein, finding it reduces S1 shedding and increases infectivity without affecting ACE2 binding or neutralization.
Nature Communications · Nov 26, 2020Peer-reviewedMicrobiology
B. D. Quinlan, W. Li, H. Mou, L. Zhang, J. Chang, S. Peng, A. Ojha, R. Tavora, M. S. Parcells, G. G. Luo, W. Li, G. Zhong, H. Choe, M. Farzan
This paper shows that an engineered RBD with glycosylation sites improves immunogenicity and expression efficiency in SARS-CoV-2 vaccines.
bioRxiv · Nov 18, 2020Microbiology
T. Ou, H. Mou, L. Zhang, A. Ojha, H. Choe, M. Farzan
This paper shows hydroxychloroquine inhibits SARS-CoV-2 entry via cathepsin L but not TMPRSS2, and that combining it with a TMPRSS2 inhibitor enhances antiviral effects.
bioRxiv · Jul 22, 2020Microbiology
B. D. Quinlan, H. Mou, L. Zhang, Y. Gao, W. He, A. Ojha, M. S. Parcells, G. Luo, W. Li, G. Zhong, H. Choe, M. Farzan
This study shows that immunization with SARS-CoV-2 RBD elicits potent neutralizing antibodies without antibody-dependent enhancement in rodents.
bioRxiv · Apr 10, 2020 · PreprintMicrobiology