Modular actin nano-architecture enables podosome protrusion and mechanosensing
K. van den Dries, L. Nahidiazar, J. A. Slotman, M. B. M. Meddens, E. Pandzic, B. Joosten, M. Ansems, J. Schouwstra, A. Meijer, R. Steen, M. Wijers, J. Fransen, A. B. Houtsmuller, P. W. Wiseman, K. Jalink, A. Cambi
This study identifies the modular actin nano-architecture of podosomes, showing how different actin modules enable protrusion and mechanosensing on varying substrate stiffness.
bioRxiv · Mar 20, 2019Cell Biology