Author

A. Cambi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. van den Dries· 4 shared B. Joosten· 3 shared A. B. Houtsmuller· 1 shared A. B. van Spriel· 1 shared A. Meijer· 1 shared A. van Duffelen· 1 shared C. G. Figdor· 1 shared C. Manzo· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersCell Biology

K. van den Dries

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Chemo-mechanical Diffusion Waves Orchestrate Collective Dynamics of Immune Cell Podosomes

Z. Gong, K. van den Dries, A. Cambi, V. Shenoy

This study develops a chemo-mechanical model to explain how immune cell podosomes generate oscillatory growth and coordinated wave dynamics through actin polymerization, myosin contractility, and actin diffusion.

bioRxiv · Nov 23, 2021 · PreprintBiophysics

Characterization of the signalling modalities of prostaglandin E2 receptors EP2 and EP4 reveals crosstalk and a role for microtubules

W. Vleeshouwers, K. van den Dries, S. de Keijzer, B. Joosten, D. S. Lidke, A. Cambi

This study characterizes EP2 and EP4 signaling in myeloid cells, revealing cAMP dynamics and microtubule dependence, with EP4 primarily mediating podosome dissolution.

bioRxiv · Oct 6, 2020Immunology

Membrane receptor MerTK is a newly identified transcriptional regulator that associates to chromatin as nanoclusters during human DC differentiation

K. J. E. Borgman, G. Florez-Grau, M. A. Ricci, C. Manzo, M. Lakadamyali, A. Cambi, D. Benitez-Ribas, F. Campelo, M. F. Garcia-Parajo

This study identifies MerTK as a transcriptional regulator in human dendritic cells, showing its nuclear translocation and clustering during differentiation.

bioRxiv · Apr 16, 2020 · PreprintImmunology

Intracellular Galectin-9 controls dendritic cell function by maintaining plasma membrane rigidity

L. Querol Cano, O. Tagit, A. van Duffelen, S. Dieltjes, S. I. Buschow, T. Niki, M. Hirashima, B. Joosten, K. van den Dries, A. Cambi, C. G. Figdor, A. B. van Spriel

This study identifies intracellular Galectin-9 as essential for maintaining plasma membrane rigidity in dendritic cells, which is critical for pathogen uptake.

bioRxiv · Aug 20, 2019Cell Biology

Modular actin nano-architecture enables podosome protrusion and mechanosensing

K. van den Dries, L. Nahidiazar, J. A. Slotman, M. B. M. Meddens, E. Pandzic, B. Joosten, M. Ansems, J. Schouwstra, A. Meijer, R. Steen, M. Wijers, J. Fransen, A. B. Houtsmuller, P. W. Wiseman, K. Jalink, A. Cambi

This study identifies the modular actin nano-architecture of podosomes, showing how different actin modules enable protrusion and mechanosensing on varying substrate stiffness.

bioRxiv · Mar 20, 2019Cell Biology