Author

M. Wijtmans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 1

Frequent Co-Authors

I. J. P. de Esch· 3 shared A. Chevigne· 2 shared C. de Graaf· 2 shared H. F. Vischer· 2 shared M. Szpakowska· 2 shared R. Leurs· 2 shared A. D. Windhorst· 1 shared A. Moberg· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersPharmacology & Toxicology

I. J. P. de Esch

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3 papers

Recent·Most cited

Design, synthesis and pharmacological characterization of the first photoswitchable small-molecule agonist for the Atypical Chemokine Receptor 3

S. Berenger, J. M. Adamska, F. Deflorian, C. de Graaf, C. B. Palmer, M. Szpakowska, A. Chevigne, I. J. P. de Esch, B. Zarzycka, H. F. Vischer, M. Wijtmans, R. Leurs

This paper designs and characterizes the first photoswitchable small-molecule agonist for ACKR3, showing its selectivity and light-controlled activation properties.

bioRxiv · Mar 20, 2024Pharmacology & Toxicology

Pharmacological characterization and radiolabeling ofVUF15485, a high-affinity small-molecule agonist for theatypical chemokine receptor ACKR3

A. Zarca, I. Adlere, C. P. Viciano, M. Arimont-Segura, M. Meyrath, I. A. Simon, J. P. M. Bebelman, D. Laan, H. G. J. Custers, E. C. Janssen, K. L. Versteegh, R. Bosma, I. J. P. De Esch, H. F. Vischer, M. Wijtmans, , R. Leurs

This paper characterizes VUF15485, a high-affinity ACKR3 agonist, and reports its radiolabeling and binding properties.

bioRxiv · Jul 12, 2023Pharmacology & Toxicology

Multiplexed experimental strategies for fragment library screening using SPR biosensors

E. A. FitzGerald, D. Vagrys, G. Opassi, H. F. Klein, D. J. Hamilton, P. Boronat, D. Cederfelt, V. O. Talibov, M. Abramsson, A. Moberg, M. T. Lindgren, C. Holmgren, D. Dobritzsch, B. Davis, P. O'Brien, , U. H. Danielson

The paper presents multiplexed SPR biosensor strategies for fragment library screening, improving hit identification for challenging targets.

bioRxiv · Dec 23, 2020 · PreprintBiophysics