Author

B. Zarzycka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. de Graaf· 2 shared R. Leurs· 2 shared A. Chevigne· 1 shared C. Aljamous· 1 shared C. B. Palmer· 1 shared C. BECHARA· 1 shared C. Leyrat· 1 shared E. Del Nero· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. de Graaf

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2 papers

Recent·Most cited

Design, synthesis and pharmacological characterization of the first photoswitchable small-molecule agonist for the Atypical Chemokine Receptor 3

S. Berenger, J. M. Adamska, F. Deflorian, C. de Graaf, C. B. Palmer, M. Szpakowska, A. Chevigne, I. J. P. de Esch, B. Zarzycka, H. F. Vischer, M. Wijtmans, R. Leurs

This paper designs and characterizes the first photoswitchable small-molecule agonist for ACKR3, showing its selectivity and light-controlled activation properties.

bioRxiv · Mar 20, 2024Pharmacology & Toxicology

Conformational dynamics underlying Atypical Chemokine Receptor 3 activation

O. Otun, C. Aljamous, E. Del Nero, M. Arimont-Segura, R. Bosma, B. Zarzycka, T. Girbau, C. Leyrat, C. de Graaf, R. Leurs, T. Durroux, S. Granier, X. Cong, C. BECHARA

This study investigates the conformational dynamics of ACKR3 activation using HDX-MS and molecular dynamics simulations, revealing key structural changes and ligand binding mechanisms.

bioRxiv · Jul 17, 2023 · PreprintBiochemistry