Author

M. Zuo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Pu· 2 shared J. L. Gommerman· 2 shared L. C. Osborne· 2 shared N. Fettig· 2 shared V. Ramaglia· 2 shared A. Gutierrez· 1 shared A. Paulucci-Holthauzen· 1 shared A. Polyzois· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

A. Pu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mining for disease-associated microbial metabolites in an age-dependent model of multiple sclerosis

A. Pu, N. Fettig, A. Polyzois, G. Chao, I. Naouar, L. Hohman, M. A. Fontaine, M. Zuo, K. Champagne-Jorgensen, J. Copeland, D. Chan, K. M. Davis, R. Yu, S. Popple, N. A. Carranza Garcia, , L. C. Osborne

The paper identifies a microbial metabolite, indole 3-propionic acid, that can reverse non-remitting EAE in aged mice, suggesting therapeutic potential for progressive MS.

bioRxiv · May 27, 2024 · PreprintImmunology

Vesicle-mediated mitochondrial clearance underlies an actionable metabolic vulnerability in triple-negative breast cancer

J. Vykoukal, Y. Chen, M. J. Hong, M. Zuo, H. Krishna, H. Katayama, E. Irajizad, R. Wu, R. Leon-Letelier, J. B. Dennison, A. Gutierrez, A. Paulucci-Holthauzen, T. C. Thompson, L. Rusling, Y. Cai, , J. F. Fahrmann

The paper identifies a metabolic vulnerability in triple-negative breast cancer through sphingolipid metabolism, showing that targeting this pathway with eliglustat reduces tumor growth and improves survival.

bioRxiv · Apr 4, 2024 · PreprintCancer Biology

Glioma-associated fibroblasts promote glioblastoma resistance to temozolomide through CCL2-CCR2 paracrine signaling

M. Zuo, S. Zhang, S. Chen, Y. Xiang, Y. Yuan, T. Li, W. Yang, Z. Wang, Y. He, W. Li, W. Feng, N. Chen, Y. Yang, Y. Zeng, Q. Mao, , y. Liu

This paper shows that glioma-associated fibroblasts enhance glioblastoma resistance to temozolomide by secreting CCL2, which activates the ERK1/2 pathway in cancer cells.

bioRxiv · Mar 5, 2024 · PreprintCancer Biology

Age related susceptibility to grey matter demyelination and neurodegeneration is associated with meningeal neutrophil accumulation in an animal model of Multiple Sclerosis

M. Zuo, N. Fettig, L.-P. Bernier, E. Possnecker, S. Spring, A. Pu, X. I. Ma, D. S. Lee, L. Ward, A. Sharma, J. Kuhle, J. G. Sled, A.-K. Probstel, B. A. MacVicar, L. C. Osborne, , V. Ramaglia

The paper shows that age-related grey matter demyelination and neurodegeneration in MS are linked to meningeal neutrophil accumulation in an animal model.

bioRxiv · Dec 23, 2021 · PreprintImmunology