CspZ FH-binding sites as epitopes promote antibody-mediated Lyme borreliae clearance
Y.-L. Chen, A. L. Marcinkiewicz, T. A. Nowak, R. T. Kundu, Z. Liu, U. Strych, M.-E. Bottazzi, W.-H. Chen, Y.-P. Lin
The paper shows that antibodies targeting CspZ FH-binding sites effectively clear Lyme borreliae in vitro and in vivo, highlighting their importance for vaccine development.
bioRxiv · May 24, 2022Immunology