Author

Madeleine Wacker

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

David MengeliD· 2 shared Matthis SynofzikiD· 2 shared Benjamin DannenmanniD· 1 shared Gülin ÖziD· 1 shared Hayley S. McLoughliniD· 1 shared Isabel G. WellikiD· 1 shared Julia SkokowaiD· 1 shared Kristen H. SchusteriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

David MengelORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Most L1CAM is not associated with extracellular vesicles in human biofluids and iPSC-derived neurons

Vaibhavi Kadam, Madeleine Wacker, Patrick Oeckl, Milena Korneck, Benjamin Dannenmann, Julia Skokowa, Stefan Hauser, Markus Otto, Matthis Synofzik, David Mengel

The paper validates EV isolation from multiple biofluids using orthogonal methods but finds L1CAM does not reliably enrich for neuron-derived EVs.

Molecular Neurobiology · Apr 10, 2025Peer-reviewedNeuroscience

Blood neurofilament light chain levels are associated with disease progression in a transgenic SCA3 mouse model

David Mengel, Isabel G. Wellik, Kristen H. Schuster, Sabrina I. Jarrah, Madeleine Wacker, Naila S. Ashraf, Gülin Öz, Matthis Synofzik, Maria do Carmo Costa, Hayley S. McLoughlin

The paper measures blood neurofilament light chain (NfL) levels in a transgenic SCA3 mouse model and finds they correlate with disease progression and severity.

bioRxiv · Feb 28, 2023 · PreprintNeuroscience