Laura A. Mike

This study identifies LPS and Wzi as factors retaining CPS on K. pneumoniae and shows their importance for bloodstream survival.

The paper introduces PULLI, a computer vision platform that extracts phenotypes from bacterial growth timelapses, revealing genotype-phenotype relationships in Vibrio cholerae mutants.

This study shows that sugar import, not catabolism, suppresses mucoidy in hypervirulent K. pneumoniae via cAMP-CRP signaling, reducing rmpADC promoter activity and rmpD expression.

This study examines phenotypic heterogeneity and environmental regulation of urovirulence in Klebsiella pneumoniae UTI isolates, finding high phenotypic variability and shared colonization ability.

This study compares the pathogenic potential of classical and hypervirulent K. pneumoniae strains producing the K2 capsule, revealing differences in tissue tropism and mucoidy despite similar capsule production.

This study identifies arginine as a key regulator of mucoidy in hypervirulent Klebsiella pneumoniae, showing it activates the rmpADC promoter and modulates capsular polysaccharide chain length, impacting immune evasion and in vivo fitness.