A Human Recombinant Antibody Against DRP1 Serine 616 Phosphorylation Enables Detection of BRAFV600E-Associated Mitochondrial Division in Cancer
Shanon Nizard, Yiyang Chen, Madhavika N. Serasinghe, Rubén Fernández‐Rodríguez, Kamrin D. Shultz, Jesminara Khatun, Anthony Mendoza, Jesse D. Gelles, Juan F. Henao-Martinez, Ioana Abraham‐Enachescu, Md Abdullah Al Noman, Stella G. Bayiokos, J. Andrew Duty, Shane Meehan, Mihaela Skobe, Jerry E. Chipuk
This paper develops a human recombinant antibody (3G11) specific for DRP1-S616 phosphorylation, demonstrating its utility in detecting mitochondrial division in cancer, particularly in BRAFV600E-associated diseases.
Antibodies · Apr 20, 2026Peer-reviewedCancer Biology