High-resolution photocatalytic crosslinking of protein neighborhoods using contact-dependent antibody mapping (contactMAP)
Johnathan C. Maza, Trenton M. Peters-Clarke, Yifei Chen, Sruthi Raguveer, Paul Burroughs, SUN Le, Madison Seto, Kevin Leung, James A. Wells
The paper introduces contactMAP, a photocatalytic crosslinking method for high-resolution mapping of protein neighborhoods, showing it rivals or outperforms existing photo-PLP methods.
bioRxiv · Jun 19, 2026 · PreprintCancer Biology