COG5-mediated Golgi organization coordinates neural progenitor fate during human brain development
Martina Polenghi, Elena Restelli, Andrea Jáñez Pedrayes, Bart Ghesquière, Maura Galimberti, Valentina Rava, Giulia Visani, Salma Amin, Cristina Cheroni, Roberta Bosotti, Sara Terzoli, Ikram Taleb-Arrada, O. Prodhomme, Fanny Alkar, Magdalena Mezaros, , Elena Taverna
This study shows that COG5 deficiency disrupts Golgi organization and affects neural progenitor fate during human brain development through altered trafficking and glycosylation.
bioRxiv · Oct 29, 2026 · PreprintCell Biology