Author

Salma Amin

Human TechnopoleORCID 0000-0002-3744-7442Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Elena TavernaiD· 2 shared Adrián CárdenasiD· 1 shared Alexandre EspinósiD· 1 shared Andrea Jáñez PedrayesiD· 1 shared ANNA CASCIO· 1 shared Arnaud BruneeliD· 1 shared Bart GhesquièreiD· 1 shared Carmen Streicher· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

Elena TavernaORCID

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3 papers

Recent·Most cited

COG5-mediated Golgi organization coordinates neural progenitor fate during human brain development

Martina Polenghi, Elena Restelli, Andrea Jáñez Pedrayes, Bart Ghesquière, Maura Galimberti, Valentina Rava, Giulia Visani, Salma Amin, Cristina Cheroni, Roberta Bosotti, Sara Terzoli, Ikram Taleb-Arrada, O. Prodhomme, Fanny Alkar, Magdalena Mezaros, , Elena Taverna

This study shows that COG5 deficiency disrupts Golgi organization and affects neural progenitor fate during human brain development through altered trafficking and glycosylation.

bioRxiv · Oct 29, 2026 · PreprintCell Biology

An improved CRISPR-LICHT screen of 120 Tdark genes illuminates new biologically relevant SOX2 targets in human brain organoids

Giorgia Pozzolini, Simon Haendeler, Salma Amin, Roberta Baldi, ANNA CASCIO, Frank Edenhofer, Elena Taverna, Christopher Esk, Veronica Krenn, Silvia K. Nicolis

The paper uses CRISPR-LICHT to screen SOX2 targets in human brain organoids, identifying 28 new genes involved in neural progenitor lineage expansion and survival.

bioRxiv · Oct 27, 2026 · PreprintDevelopmental Biology

Early Indirect Neurogenesis transitions to late Direct Neurogenesis in mouse cerebral cortex development

Adrián Cárdenas, Irem Celik, Alexandre Espinós, Carmen Streicher, Lara López-González, Lena Anton, Virginia Fernández, Salma Amin, Enrico Negri, Eduardo Fernández Ortuño, Simon Hippenmeyer, Vı́ctor Borrell

The paper challenges the established model of cortical neurogenesis by showing indirect neurogenesis predominates early and shifts to direct neurogenesis later in mouse cerebral cortex development.

bioRxiv · May 22, 2025 · PreprintNeuroscience