Maja Milas

Crowding governs resistance confinement and guides the improvement of adaptive therapy in a 2D melanoma model system

This study shows how mechanical crowding in 2D melanoma models influences resistance expansion and therapy failure, guiding adaptive therapy improvement through physical and computational models.

Heterogeneity in environmental stiffness alone can guide cells and shape tissues

This study shows that cells can be guided and tissues shaped by environmental stiffness heterogeneity alone, without topographical or chemical cues.