Carlos Ureña Martín

Heterogeneity in environmental stiffness alone can guide cells and shape tissues

This study shows that cells can be guided and tissues shaped by environmental stiffness heterogeneity alone, without topographical or chemical cues.

Effect of the Environmental Mechanical Heterogeneity on T Cell Function

This study shows that T cells respond to mechanical heterogeneity by not averaging signals, leading to lower activation than on stiff surfaces, but long-term exposure enhances memory and effector T cell proliferation.

Mechanical stress and caveolin-1 control the release of extracellular vesicles with increased tumorigenic properties

This study shows mechanical stress increases EV release from cancer cells via caveolin-1, leading to more tumorigenic EVs that promote metastasis.