Development of a Targeted Choroidal Injury Model for the Study of Retinal Degenerations and Therapeutic Cell Replacement
Narendra G. Pandala, Lorena De Melo Haefeli, Mallory J. Lang, Edwin M. Stone, Robert F. Mullins, Budd A. Tucker, Ian C. Han
This paper develops a targeted choroidal injury model in rats using saporin-conjugated antibodies and compares it to systemic sodium iodate administration, showing localized injury with fewer side effects.
Translational Vision Science & Technology · Aug 20, 2026Peer-reviewedNeuroscience