Author

Laura R. Bohrer

University of Iowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:organoid / primary culture· 1 Organism:rat· 1

Frequent Co-Authors

Budd A. TuckeriD· 4 shared Edwin M. StoneiD· 4 shared Robert F. MullinsiD· 4 shared Allison T. Wright· 3 shared Nathaniel K. MulliniD· 3 shared Ian C. HaniD· 2 shared Alexander Berthold· 1 shared Andrew P. VoigtiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersNeuroscience

Budd A. TuckerORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Production of clinical grade patient iPSC-derived 3D retinal organoids containing transplantable photoreceptor cells

Laura R. Bohrer, Luke A. Wiley, Allison T. Wright, Bradley Hittle, Mallory J. Lang, Louisa M. Affatigato, Kimerly A. Powell, Lorena De Melo Haefeli, Ian C. Han, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker

This study develops a xeno-free 3D retinal differentiation protocol for iPSCs to generate transplantable photoreceptor cells in a cGMP-compliant manner.

Stem Cell Research & Therapy · Nov 17, 2025Peer-reviewedNeuroscience

Device-free isolation of photoreceptor cells from patient iPSC-derived retinal organoids

Nicholas E. Stone, Laura R. Bohrer, Nathaniel K. Mullin, Alexander Berthold, Allison T. Wright, Ian C. Han, Edwin M. Stone, Robert F. Mullins, Budd A. Tucker

This paper describes a method to isolate photoreceptor cells from retinal organoids without specialized equipment, using standard lab materials for potential clinical applications.

JCI Insight · Jun 12, 2025Peer-reviewedBioengineering

Exonic splice variant discovery using in vitro models of inherited retinal disease

Nathaniel K. Mullin, Laura R. Bohrer, Kristin R. Anfinson, Jeaneen L. Andorf, Robert F. Mullins, Budd A. Tucker, Edwin M. Stone

The paper identifies a splice defect caused by the NR2E3 c.932G>A variant in retinal disease, challenging previous assumptions about its molecular mechanism.

Human Genetics and Genomics Advances · Sep 30, 2024Peer-reviewedGenetics

Loss of NR2E3 disrupts rod photoreceptor cell maturation causing a fate switch late in human retinal development.

Nathaniel K. Mullin, Laura R. Bohrer, Andrew P. Voigt, Lola P. Lozano, Allison T. Wright, Robert F. Mullins, Edwin M. Stone, Budd A. Tucker

This study uses human retinal organoids to show that loss of NR2E3 disrupts rod photoreceptor maturation, leading to a fate switch to cone-like cells.

bioRxiv · Jun 30, 2023 · PreprintDevelopmental Biology