Ian C. Han

This paper develops a targeted choroidal injury model in rats using saporin-conjugated antibodies and compares it to systemic sodium iodate administration, showing localized injury with fewer side effects.

This study evaluates polyurethane nanocapsules delivering Acriflavine for treating CNVM in a rat model, showing reduced CNVM size and incidence compared to controls.

This study develops a xeno-free 3D retinal differentiation protocol for iPSCs to generate transplantable photoreceptor cells in a cGMP-compliant manner.

This paper describes a method to isolate photoreceptor cells from retinal organoids without specialized equipment, using standard lab materials for potential clinical applications.

This paper develops self-healing hydrogels to support choroidal endothelial cell transplantation in a rat model, showing improved cell retention compared to cell suspensions.

This study uses spatial transcriptomics to analyze gene expression in a human choroidal neovascular membrane and identifies dysregulated genes and potential upstream regulators.