Development of a Targeted Choroidal Injury Model for the Study of Retinal Degenerations and Therapeutic Cell Replacement
Narendra G. Pandala, Lorena De Melo Haefeli, Mallory J. Lang…·Ian C. Han
This paper develops a targeted choroidal injury model in rats using saporin-conjugated antibodies and compares it to systemic sodium iodate administration, showing localized injury with fewer side effects.