Author

Manon Farcé

Centre de Recherches en Cancérologie de Toulouse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Lætitia Ligat· 2 shared Alban Ricard· 1 shared Alexandre StellaiD· 1 shared Chloe Bazile· 1 shared Claire VargasiD· 1 shared Corinne BousquetiD· 1 shared Damien Varry· 1 shared Dorian Larrieu· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Lætitia Ligat

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2 papers

Recent·Most cited

Targeting human M2 macrophages with antibodies in optimized 3D tumor spheroids

Chloe Bazile, Fabien Gava, Flavien Raynal, Marcin Domagala, Julie Bordenave, Lætitia Ligat, Manon Farcé, Corinne Bousquet, Véra Pancaldi, Véronique Gigoux, Mary Poupot

This study develops an in vitro 3D tumor spheroid model to target pro-tumoral macrophages with antibodies, showing effective killing even in spheroid centers.

bioRxiv · Sep 16, 2025 · PreprintCancer Biology

The intrinsically disordered region of the E3 ubiquitin ligase TRIP12 induces the formation of chromatin condensates and interferes with DNA damage response.

Claire Vargas, Manon Brunet, Alban Ricard, Damien Varry, Dorian Larrieu, Fernando Muzzopappa, Fabian Erdel, Guillaume Labrousse, Naïma Hanoun, Lætitia Ligat, Manon Farcé, Alexandre Stella, Odile Burlet‐Schiltz, Henrik Laurell, Nicolas Béry, , Jérôme Torrisani

This study shows TRIP12's intrinsically disordered region drives chromatin condensate formation, disrupting DNA damage response and genome accessibility.

bioRxiv · Sep 13, 2023 · PreprintMolecular Biology