A combinatorial EVs-miRNA signature mediates the anti-tumoral activity of NFAT3-regulated extracellular vesicles in aggressive cancers.
Guenole Tossou, Nadia Ourari, Maëlle Ralu, Alexandre Montanede, Frédéric Guaddachi, Babette Beher, Manon Paul, Emilie Ouanounou, Morgane Le Bras, Stéphane Brunet, Jacqueline Lehmann‐Che, Sébastien Jauliac
The paper identifies a combinatorial miRNA signature in EVs regulated by NFAT3 that suppresses tumor aggressiveness in TNBC and pancreatic cancer models.
Molecular Therapy · Jul 30, 2026Peer-reviewedCancer Biology