Alu-mediated weak CEBPA binding and slow B cell transdifferentiation in human
Ramil Nurtdinov, María Sanz, Amaya Abad, Alexandre Esteban, Sebastian Ullrich, Carme Arnan, Rory Johnson, Sílvia Pérez-Lluch, Roderic Guigó
The paper identifies weak CEBPA binding in humans as a cause of slower B cell transdifferentiation compared to mice, linked to Alu repeat expansions.
bioRxiv · Oct 28, 2021 · PreprintBioinformatics