Association with TFIIIC limits MYCN localization in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA Polymerase II
Raphael Silveira Vidal, Eoin N. Leen, Steffi Herold, Mareike Müller, Daniel Fleischhauer, Christina Schülein‐Völk, Dimitrios Papadopoulos, Isabelle Röschert, Leonie Uhl, Carsten Patrick Ade, Peter Gallant, Richard W. Bayliss, Martin Eilers, Gabriele Büchel
The paper shows that TFIIIC binds MYCN and limits non-phosphorylated RNA Polymerase II accumulation at promoters, but does not affect MYCN-dependent gene expression or transcription elongation.
eLife · Feb 7, 2024Peer-reviewedMolecular Biology