Author

Daniel Fleischhauer

University of Leeds

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Dimitrios PapadopoulosiD· 2 shared Gabriele BücheliD· 2 shared Leonie UhliD· 2 shared Martin EilersiD· 2 shared Raphael Silveira VidaliD· 2 shared Richard W. BaylissiD· 2 shared Carsten Patrick AdeiD· 1 shared Christina Schülein-Völk· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Dimitrios PapadopoulosORCID

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2 papers

Recent·Most cited

The MYCN/Aurora-A complex is a cyclin activating kinase for CDK12

Mareike Müller, Lorenz Eing, Leonie Uhl, Maximilian Schmitz, Iliyana N. Kaneva, Dominic P. Byrne, Daniel Fleischhauer, Selena G. Burgess, Sophia Fischer, N Gebauer, Vanessa Nancy-Portebois, Ines H. Kaltheuner, Stefanie Ahn Ha, Christina Schülein-Völk, Daniel Solvie, , Gabriele Büchel

This study identifies Aurora-A as a CDK12-activating kinase in neuroblastoma, showing its role in transcription termination and tumor growth suppression.

bioRxiv · Jan 15, 2025 · PreprintCancer Biology

Association with TFIIIC limits MYCN localization in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA Polymerase II

Raphael Silveira Vidal, Eoin N. Leen, Steffi Herold, Mareike Müller, Daniel Fleischhauer, Christina Schülein‐Völk, Dimitrios Papadopoulos, Isabelle Röschert, Leonie Uhl, Carsten Patrick Ade, Peter Gallant, Richard W. Bayliss, Martin Eilers, Gabriele Büchel

The paper shows that TFIIIC binds MYCN and limits non-phosphorylated RNA Polymerase II accumulation at promoters, but does not affect MYCN-dependent gene expression or transcription elongation.

eLife · Feb 7, 2024Peer-reviewedMolecular Biology