Epigenetic derepression of FKBP5 by aging and stress contributes to NF-kB-driven inflammation and cardiovascular risk
Anthony S. Zannas, Meiwen Jia, Kathrin Hafner, Jens J Baumert, Tobias Wiechmann, Julius C. Pape, Janine Arloth, Maik Ködel, Silvia Martinelli, Maria Roitman, Simone Röh, Andreas Haehle, Rebecca T. Emeny, Stella Iurato, Tania Carrillo‐Roa, , Elisabeth B. Binder
The paper identifies FKBP5 epigenetic derepression by aging and stress as a driver of NF-kB-driven inflammation and cardiovascular risk through in vitro and cohort studies.
bioRxiv · Dec 3, 2018 · PreprintGenomics